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M9550222.TXT
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1995-03-04
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Document 0222
DOCN M9550222
TI Application of the polymerase chain reaction for the detection of HIV in
specimens from newborn screening programs.
DT 9505
AU Comeau AM; Theobald Smith Research Institute, Inc., State Laboratory;
Institute, Jamaica Plain, MA.
SO Acta Paediatr Suppl. 1994 Aug;400:29-30. Unique Identifier : AIDSLINE
MED/95135014
AB The use of the polymerase chain reaction (PCR) permits detection of HIV
proviral DNA in the universally collected dried blood spot specimens of
newborn screening programs. Detection of HIV proviral DNA among the
annual cohorts of seropositive specimens from ongoing anonymous newborn
HIV seroprevalence studies can provide a laboratory-based estimate of
maternal-infant transmission rates. Preliminary data suggest that
maternal-infant transmission rates may be higher in areas where the
newborn seroprevalence rates are highest.
DE Disease Transmission, Vertical DNA, Viral/*ANALYSIS Human HIV
Seropositivity/BLOOD/*DIAGNOSIS/GENETICS/TRANSMISSION Infant, Newborn
*Neonatal Screening *Polymerase Chain Reaction Support, U.S. Gov't,
P.H.S. JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).